Philadelphia International Airport (PHL) passengers seeking a Caribbean or Mexican getaway have 16 nonstop year-round and seasonal options:

Aguadilla (BQN)
Aruba (AUA) 
Bermuda (BDA) 
Grand Cayman (GCM)
Montego Bay, Jamaica (MBJ) 
Nassau, Bahamas (NAS) 
Providenciales, Turks and Caicos (PLS) 
Punta Cana, Dominican Republic (PUJ) 
Santo Domingo, Dominican Republic (SDQ) 
Santiago, Dominican Republic (STI) 
St. Maarten (SXM) 
St. Lucia (UVF) 
St. Thomas (STT)
San Juan (SJU)
Cancun (CUN) 
Cozumel (CZM)